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Forschung & Lehre

Klinische Publikationen

Glanzlichter biomedizinischer Forschung

Mit den Glanzlichtern biomedizinischer Forschung möchten wir Ihnen einen Einblick in die an der Medizinischen Fakultät der Universität Regensburg geleistete Forschung geben. Vor allem jungen Kolleginnen und Kollegen wird hier eine Plattform geboten, ihre Forschungsarbeit vorzustellen.

 

 

Aktuelles Glanzlicht - Mai 2022

Philipp Bengel, Nataliya Dybkova, Petros Tirilomis, Shakil Ahmad, Nico Hartmann, Belal A. Mohamed, Miriam Celine Krekeler, Wiebke Maurer, Steffen Pabel, Maximilian Trum, Julian Mustroph, Jan Gummert, Hendrik Milting, Stefan Wagner, Senka Ljubojevic-Holzer, Karl Toischer, Lars S. Maier, Gerd Hasenfuss, Katrin Streckfuss-Bömeke, Samuel Sossalla. Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure. Nat Commun 12, 6586 (2021).

doi: 10.1038/s41467-021-26690-1

 

Newsroom UKR: Schlüsselmechanismus für Herzrhythmusstörungen bei Herzschwäche identifiziert

  • Mai 2022:

    Philipp Bengel, Nataliya Dybkova, Petros Tirilomis, Shakil Ahmad, Nico Hartmann, Belal A. Mohamed, Miriam Celine Krekeler, Wiebke Maurer, Steffen Pabel, Maximilian Trum, Julian Mustroph, Jan Gummert, Hendrik Milting, Stefan Wagner, Senka Ljubojevic-Holzer, Karl Toischer, Lars S. Maier, Gerd Hasenfuss, Katrin Streckfuss-Bömeke, Samuel Sossalla. Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure. Nat Commun 12, 6586 (2021).

    doi: 10.1038/s41467-021-26690-1

     

    April 2022:

    Bernhard Neumann; Klemens Angstwurm, Ralf A. Linker, Gertrud Knoll, Lisa Eidenschink, Dennis Rubbenstroth, Kore Schlottau, Martin Beer, Patrick Schreiner, Erwin Soutschek, Merle M. Böhmer, Benedikt M.J. Lampl, Matthias Pregler, Alexander Scheiter, Katja Evert, Saida Zoubaa, Markus J. Riemenschneider, Benedikt Asbach, André Gessner, Hans Helmut Niller, Barbara Schmidt, Markus Bauswein. Antibodies against viral nucleo-, phospho-, and X protein contribute to serological diagnosis of fatal Borna disease virus 1 infections.

    doi: 10.1016/j.xcrm.2021.100499

     

    März 2022:

    Peter J. Siska, Sonja-Maria Decking, Nathalie Babl, Carina Matos, Christina Bruss, Katrin Singer, Jana Klitzke, Marian Schön, Jakob Simeth, Josef Köstler, Heiko Siegmund, Ines Ugele, Michael Paulus, Alexander Dietl, Kristina Kolodova, Louisa Steines, Katharina Freitag, Alice Peuker, Gabriele Schönhammer, Johanna Raithel, Bernhard Graf, Florian Geismann, Matthias Lubnow, Matthias Mack, Peter Hau, Christopher Bohr, Ralph Burkhardt, Andre Gessner, Bernd Salzberger, Ralf Wagner, Frank Hanses, Florian Hitzenbichler, Daniel Heudobler, Florian Lüke, Tobias Pukrop, Wolfgang Herr, Daniel Wolff, Rainer Spang, Hendrik Poeck, Petra Hoffmann, Jonathan Jantsch, Christoph Brochhausen, Dirk Lunz, Michael Rehli, Marina Kreutz, and Kathrin Renner. Published in Volume 131, Issue 22 on November 15, 2021  J Clin Invest. 2021;131(22):e148225.

    doi: 10.1172/JCI148225

     

    Februar 2022:

    Xiaojun Mao, Nicholas S. Jakubovics, Maria Bächle, Wolfgang Buchalla, Karl-Anton Hiller, Tim Maisch, Elmar Hellwig, Christian Kirschneck, André Gessner, Ali Al-Ahmad & Fabian Cieplik (2021) Colonization of Helicobacter pylori in the oral cavity – an endless controversy?, Critical Reviews in Microbiology, 47:5, 612-629.

    doi: 10.1080/1040841X.2021.1907740

    Januar 2022:

    Meedt E, Hiergeist A, Gessner A, et al. Prolonged suppression of butyrate producing bacteria is associated with acute gastrointestinal graft-versus-host disease and transplant related mortality after allogeneic stem cell transplantation. Clin Infect Dis. Published online May 27, 2021:ciab500.

     

    doi: 10.1093/cid/ciab500

  • Dezember 2021:

    Tafelmeier M, Luft L, Zistler E, Floerchinger B, Camboni D, Creutzenberg M, Zeman F, Schmid C, Maier LS, Wagner S, Arzt M. Central Sleep Apnea Predicts Pulmonary Complications After Cardiac Surgery. Chest. 2021 Feb;159(2):798-809.

    doi: 10.1016/j.chest.2020.07.080

     

    November 2021:

    Renner, K., Schwittay, T., Chaabane, S. et al. Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes. Nat Commun. 2021 May 21;12(1):3006

    doi: https://doi.org/10.1038/s41467-021-23334-2 

     

    Oktober 2021:

    Julian Mustroph, Can M. Sag, Felix Bähr, Anna-Lena Schmidtmann, Shamindra N. Gupta, Alexander Dietz, M.M. Towhidul Islam, Charlotte Lücht, Bo Eric Beuthner, Steffen Pabel, Maria J. Baier, Ali El-Armouche, Samuel Sossalla, Mark E. Anderson, Julia Möllmann, Michael Lehrke, Nikolaus Marx, Peter J. Mohler, Donald M. Bers, Bernhard Unsöld, Tao He, Matthias Dewenter, Johannes Backs, Lars S. Maier, Stefan Wagner. Loss of CASK Accelerates Heart Failure Development, Circulation Research. 2021;128:1139–1155.

    doi: https://doi.org/10.1161/CIRCRESAHA.120.318170

     

    September 2021:

    Maria Xydia, Raheleh Rahbari, Eliana Ruggiero, Iain Macaulay, Maxime Tarabichi, Robert Lohmayer, Stefan Wilkening, Tillmann Michels, Daniel Brown, Sebastian Vanuytven, Svetlana Mastitskaya, Sean Laidlaw, Niels Grabe, Maria Pritsch, Raffaele Fronza, Klaus Hexel, Steffen Schmitt, Michael Müller-Steinhardt, Niels Halama, Christoph Domschke, Manfred Schmidt, Christof von Kalle, Florian Schütz, Thierry Voet and Philipp Beckhove. Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients. Nat Commun 12, 1119 (2021). 

    doi: https://doi.org/10.1038/s41467-021-21297-y

     

    August 2021:

    Zhang J. , Byers P. , Erben A. , Frank C. , Schulte-Spechtel L. , Heymann M. , Docheva D. , Huber H. , Sudhop S. , Clausen-Schaumann H. "Single Cell Bioprinting with Ultrashort Laser Pulses" Advanced Functional Materials. 2021 Mar 26

    doi: https://doi.org/10.1002/adfm.202100066

     

    Juli 2021:

    Delacher M, Simon S, Sanderink L, Hotz-Wagenblatt A, Wuttke M, Schambeck K, Schmidleithner L, Bittner S, Pant A, Ritter U, Hehlgans T, Riegel D, Schneider V, Groeber-Becker FK, Eigenberger A, Gebhard C, Strieder N, Fischer A, Rehli R, Hoffmann P, Edinger M, Strowig T, Huehn J, Schmidl C, Werner JM, Prantl L, B Brors B, Imbusch CD, Feuerer M. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity , 2021

    doi: https://www.sciencedirect.com/science/article/pii/S1074761321001199?via%3Dihub

     

    Juni 2021:

    Haderer M, Neubert P, Rinner E, Scholtis A, Broncy L, Gschwendtner H, Kandulski A, Pavel V, Mehrl A, Brochhausen C, Schlosser S, Gülow K, Kunst C, Müller M. Novel pathomechanism for spontaneous bacterial peritonitis: Disruption of cell junctions by cellular and bacterial proteases. Gut 2021.

    doi: https://doi.org/10.1136/gutjnl-2020-321663

     

    Mai 2021:

    Haferkamp, S, Hutchinson, J A et al.: "Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis." Nat Commun 12, 1439 (2021).

    doi: https://doi.org/10.1038/s41467-021-21572-y

     

    April 2021:

    Hansen, Ernil et al.: "Effect of therapeutic suggestions during general anaesthesia on postoperative pain and opioid use: multicentre randomised controlled trial." BMJ 2020 Dec 10; 371:m4284.

    doi:  https://doi.org/10.1136/bmj.m4284

    Editorial: Boet, S & McIsaac, DI: "Can We Sooth the Subconscious during General Anaesthesia?" BMJ 2020 Dec 10; 371:m4547.

    doi: https://doi.org/10.1136/bmj.m4547

     

    März 2021:

    Corbacioglu, Selim et al.: "CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia" in: N Engl J Med. 2020, Dec 5.

    doi: 10.1056/NEJMoa2031054 

     

    Februar 2021:

    Werner-Klein, Melanie et al.: "Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency" in: Nature Communications 2020, Oct. 2020.

    doi: https://doi.org/10.1038/s41467-020-18701-4

     

    Januar 2021:

    Kerkhoff, Eugen et al.: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins" in Nat Commun. Published: July 13, 2020.

    doi: 10.1038/s41467-020-17212-6